In the blind end of the coronary artery. 2 Results According to the above criteria and classification methods, the results of 186 patients were shown in Table 1. Table 1 186 patients with genotype I type la type male and female total from the above results showed that contrast agent adherence type is the most common, followed by It is type I, and again it is type I. 3 Discussion In coronary angiography, the left and right coronary blood flow velocity of the normal coronary artery is about the same, about 1.5 cardiac cycles to empty the contrast agent; the left anterior descending artery contrast agent emptying speed is about 1 75 cardiac cycles. We found that contrast agents were retained for more than 3 cardiac cycles in patients with delayed contrast emptying. The type I of the contrast agent forming a slow blood flow may be associated with coronary microangiopathy, and the coronary microvascular resistance is increased, resulting in retention of the contrast agent in the blood vessel. It is confirmed by animal experiments that the phenomenon of slow blood flow in rabbit abdominal aorta is closely related to endothelial cell injury. Slow blood flow may be a new pathogenesis of ischemic heart disease, which represents both the early stages of atherosclerosis and endothelial dysfunction, and also suggests microvascular dysfunction. Endothelial dysfunction is a triggering factor in atherosclerosis. During the development of atherosclerosis, endothelial dysfunction occurs earlier than coronary angiographic abnormalities and clinical symptoms. Therefore, the detection of endothelial dysfunction is an important early diagnosis index 2~41. The type of contrast agent adherence may be related to the decrease of coronary artery compliance and the decrease of coronary systolic function. The specific mechanism remains unclear. Further clinical and experimental research. The curved portion of the contrast agent retained in the lit type may be related to the hydrodynamic changes in blood flow, but it is difficult to interpret the contrast agent retention in the normal but not curved portion. The im-type and nt-type contrast agents are caused by stenosis and occlusion of the lesion. Among them, the clinical significance of type I, type I and it type needs further study.
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